Sexuality and sickle cell anemia

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Sexuality and sickle cell anemia

BACKGROUND Sickle cell disease, the most common hereditary blood disease in the world, is the result of an atypical hemoglobin called S (Hb S) which, when homozygous (Hb SS) is the cause of sickle cell anemia. Changes of puberty, correlated with a delayed growth spurt, begin late in both male and female sickle cell anemia individuals with repercussions on sexuality and reproduction. The objecti...

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Sexuality and sickle cell disease

DOI: 10.5581/1516-8484.20130021 For decades, sickle cell disease (SCD) was mainly considered a childhood disease, since until 1973 life expectancy was 14 years(1). However, most children with SCD outlive this barrier(2). Newborn screening, prophylactic penicillin, and effective vaccinations against Haemophilus influenzae type b and Streptococcus pneumonia are some of the factors responsible for...

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Side Effects of Hydroxyurea in Patients with Sickle Cell Anemia

Background: Hemoglobin S arises is the result of a point mutation (A-T) in the sixth codon on the -globin gene on chromosome 11 causing sickle cell anemia. The presence of fetal hemoglobin in infancy plays a relatively protective role for vaso-occlusive symptoms that are the major contributor for the morbidity and mortality among patients with sickle cell anemia. hydroxyurea, an s-phase-specif...

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ژورنال

عنوان ژورنال: Revista Brasileira de Hematologia e Hemoterapia

سال: 2013

ISSN: 1516-8484

DOI: 10.5581/1516-8484.20130027